Cane Bay’s Kris Copeland rushed for more than 300 yards and five touchdowns as the Cobras handed Beaufort High its second straight loss, 49-33 on Friday.
Jeffrey Smyth scored three rushing touchdowns for the Eagles, who were without leading rusher Kyleik Middleton.
Beaufort (6-2, 2-2) can clinch the No. 3 seed in the playoffs with a win at Hilton Head High next week, but the Eagles also could slip into a three-way tie for the final two playoff spots with a loss to the Seahawks.