Beaufort Academy was within a field goal in the fourth quarter before injuries derailed the offense and the Eagles fell on the road to a tough Clarendon Hall team on Friday.
DeShawn Epps rushed for 215 yards and two touchdowns in his BA debut, and Dawson Coleman was 13-for-17 for 231 yards and two touchdowns.
Daniel Richards caught six passes for 86 yards, and Charlie Weeden and DaiJion Galloway each had a touchdown receptions.
Jaxon Spratling recorded 13 tackles, and Galloway added eight to lead the defense.
BA (0-2) hosts Patrick Henry next week.