Ridgeland-Hardeeville had the lead at halftime, but Colleton County’s offense got going in the second half en route to a 38-6 victory.
Joseph Robinson’s touchdown run gave the Jaguars a 6-3 halftime lead, but the Cougars hit their stride after the break and took control.
The Jaguars (1-4) are off next week before opening region play at May River on Oct. 11.